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State-of-the-art literature review

The state-of-the-art review establishes current knowledge on the condition and alternative treatments — a broad systematic search, exactly what AutoSearch automates: PRISMA-grade, DOI-verified, in an afternoon.

Built in Switzerland · Crossref-verified citations · 0 fabricated DOIs in our public benchmark

For an EU MDR clinical evaluation, the state-of-the-art (SOTA) review is a broad systematic literature review of the medical condition, current standard of care and alternatives — not of your device. That breadth is precisely where a fast, multi-database, reproducible engine shines. AutoSearch runs the SOTA search, screens it and documents it to PRISMA, with verifiable sources.

Broad, systematic, reproducible

AutoSearch searches OpenAlex, Crossref, PubMed, Semantic Scholar and ClinicalTrials.gov in parallel for the condition, standard of care and alternative treatments, screens each record with a recorded decision, and outputs a PRISMA 2020 flow, an evidence matrix, inline citations and a screening log — a defensible SOTA evidence base.

An under-served, winnable topic

Few tools target the SOTA review specifically; most content is consultancy how-tos. A precise page plus a working, self-service tool wins this long-tail — and feeds directly into your CER's state-of-the-art section.

Verifiable and repeatable

Every DOI is checked live against Crossref (0 fabricated in our benchmark), and the stored protocol re-runs for periodic SOTA updates under MDR / IVDR.

What the SOTA review needs, and what AutoSearch delivers
SOTA review needAutoSearch
Broad condition/therapy searchParallel multi-database search beyond the device itself.
Standard of care & alternativesWide evidence capture with documented protocol.
Documented screeningRecorded keep/discard reason; exportable CSV log.
PRISMA flow & evidence basePRISMA 2020 flow and typed evidence matrix automatically.
Verifiable sourcesEvery DOI live-checked against Crossref; 0 fabricated.

Frequently asked questions

What is a state-of-the-art review in a CER?

It is a broad systematic literature review of the medical condition, the current standard of care and alternative treatments — establishing the clinical context against which your device is evaluated. AutoSearch automates the search, screening and PRISMA documentation.

Is it different from the device literature search?

Yes. The SOTA review is about the condition and alternatives, not your specific device; its breadth suits a fast multi-database engine.

Which databases does it search?

OpenAlex, Crossref, PubMed, Semantic Scholar, arXiv, ClinicalTrials.gov, DBLP and DOAJ, in parallel.

Are the citations verified?

Yes. Every DOI is checked live against Crossref; our public benchmark reports 0 fabricated DOIs across hundreds of references.

How much does it cost?

From CHF 29/month (Researcher, 300 credits) or one-time credits; a standard review is about 8 credits, with 50 free starter credits on signup.

Run your state-of-the-art literature review

Write one research question on the condition and alternatives, and AutoSearch returns a PRISMA-grade, DOI-verified SOTA review for your clinical evaluation.

Run a free review →